BDBM50163452 2-Amino-4-(3-fluoro-phenyl)-6-(2-hydroxy-ethylsulfanyl)-pyridine-3,5-dicarbonitrile::CHEMBL179198

SMILES Nc1nc(SCCO)c(C#N)c(-c2cccc(F)c2)c1C#N

InChI Key InChIKey=DKTHVMKCQBQDIW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163452   

TargetAdenosine receptor A1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163452(2-Amino-4-(3-fluoro-phenyl)-6-(2-hydroxy-ethylsulf...)
Affinity DataKi:  39.8nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163452(2-Amino-4-(3-fluoro-phenyl)-6-(2-hydroxy-ethylsulf...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed