BDBM50164049 (Z)-But-2-enedioic acid ([2,2'']bithiophenyl-5-ylmethyl)-amide (2''-sulfamoyl-biphenyl-4-ylmethyl)-amide::CHEMBL180458

SMILES NS(=O)(=O)c1ccccc1-c1ccc(CNC(=O)\C=C/C(=O)NCc2ccc(s2)-c2cccs2)cc1

InChI Key InChIKey=ZRPHFYDFGAOSDH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164049   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164049((Z)-But-2-enedioic acid ([2,2'']bithiophenyl-5-ylm...)
Affinity DataKi:  410nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164049((Z)-But-2-enedioic acid ([2,2'']bithiophenyl-5-ylm...)
Affinity DataIC50: 520nMAssay Description:In vitro inhibitory concentration against voltage-gated sodium channel Nav1.7 in voltage-ion-probe-reader (VIPR) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed