BDBM50164470 2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfanyl}-5-methyl-phenylamine::CHEMBL195585

SMILES Cc1ccc(Sc2ccccc2CNCCCF)c(N)c1

InChI Key InChIKey=TZHJRGABGIEARJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164470   

TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi:  518nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi:  4.33E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed