BDBM50164500 CHEMBL3800091

SMILES CC(C)Cc1onc(-c2nc(no2)-c2ccc(CN3CC(C3)C(O)=O)cc2)c1C(F)(F)F

InChI Key InChIKey=KKZAKGKOIPIRBJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164500   

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50164500(CHEMBL3800091)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cell membranes after 45 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50164500(CHEMBL3800091)
Affinity DataEC50:  6.20E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in EDG3-Ga15-bla HEK293T cell membranes after 45 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2017
Entry Details Article
PubMed