BDBM50164681 CHEMBL3797529

SMILES NC(=O)c1cc(Cl)cn(Cc2ccccc2)c1=N

InChI Key InChIKey=QAAPGSLXWSJEEX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50164681   

TargetAlpha-1D adrenergic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164681(CHEMBL3797529)
Affinity DataKi:  30nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164681(CHEMBL3797529)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-HT 1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164681(CHEMBL3797529)
Affinity DataKi: >1.20E+3nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1B adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164681(CHEMBL3797529)
Affinity DataKi: >2.70E+3nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1A adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed