BDBM50164691 CHEMBL372464::N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(4-methoxy-phenyl)-5-trifluoromethyl-pyrimidine-2,4-diamine

SMILES COc1ccc(Nc2nc(Nc3ccc4nc[nH]c4c3)ncc2C(F)(F)F)cc1

InChI Key InChIKey=VMXUAXSUFHWVMR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50164691   

TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164691(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(4-methoxy-pheny...)
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164691(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(4-methoxy-pheny...)
Affinity DataIC50: 57nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164691(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(4-methoxy-pheny...)
Affinity DataIC50: 57nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164691(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(4-methoxy-pheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Extracellular signal-regulated kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed