BDBM50164797 CHEMBL3797808

SMILES CC(=O)NC(Cc1cnc[nH]1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCCC1C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)NC(Cc1cnc[nH]1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O

InChI Key InChIKey=IMIABEFKOHFRBE-UHFFFAOYSA-N

Data  3 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50164797   

TargetMelanocortin receptor 5(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164797(CHEMBL3797808)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164797(CHEMBL3797808)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164797(CHEMBL3797808)
Affinity DataEC50:  9.20nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164797(CHEMBL3797808)
Affinity DataEC50:  20nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164797(CHEMBL3797808)
Affinity DataIC50: 28nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC1R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164797(CHEMBL3797808)
Affinity DataIC50: 33nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164797(CHEMBL3797808)
Affinity DataIC50: 3.25E+3nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC3R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed