BDBM50164847 CHEMBL3799626

SMILES CN(CCCCNC(=O)c1ccc-2c(Cc3ccccc-23)c1)[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23

InChI Key InChIKey=OJVDNCHTCHUSCE-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50164847   

TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164847(CHEMBL3799626)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164847(CHEMBL3799626)
Affinity DataEC50:  12nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164847(CHEMBL3799626)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164847(CHEMBL3799626)
Affinity DataEC50:  102nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164847(CHEMBL3799626)
Affinity DataEC50:  109nMAssay Description:Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164847(CHEMBL3799626)
Affinity DataEC50:  125nMAssay Description:Agonist activity at human D3 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164847(CHEMBL3799626)
Affinity DataKi:  1.09E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164847(CHEMBL3799626)
Affinity DataKi:  3.70E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed