BDBM50165176 4-[(4R,7S,10S,13R,16S)-19-(2-azaniumyl-3-phenylpropanamido)-4-{[(2R)-1,3-dihydroxybutan-2-yl]carbamoyl}-7-(1-hydroxyethyl)-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-10-yl]butan-1-aminium::Radiolabeled octreotide derivative

SMILES CC(O)[C@@H](CO)NC(=O)[C@@H]1CSSCC(NC(=O)C([NH3+])Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCC[NH3+])C(=O)N[C@@H](C(C)O)C(=O)N1

InChI Key InChIKey=LHCIROHUTQLZCZ-UHFFFAOYSA-P

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50165176   

TargetSomatostatin receptor type 5(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165176(4-[(4R,7S,10S,13R,16S)-19-(2-azaniumyl-3-phenylpro...)
Affinity DataIC50: 10.8nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 5 expressed in CHO-K1 cells; (n=2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165176(4-[(4R,7S,10S,13R,16S)-19-(2-azaniumyl-3-phenylpro...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 3 expressed in CCL39 cells; (n=2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165176(4-[(4R,7S,10S,13R,16S)-19-(2-azaniumyl-3-phenylpro...)
Affinity DataIC50: 346nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 4 expressed in CCL39 cells; (n=2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165176(4-[(4R,7S,10S,13R,16S)-19-(2-azaniumyl-3-phenylpro...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against somatostatin receptor type 1 expressed in CHO-K1 cells using [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165176(4-[(4R,7S,10S,13R,16S)-19-(2-azaniumyl-3-phenylpro...)
Affinity DataIC50: 3.10nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 5 expressed in CHO-K1 cells; (n=2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed