BDBM50165323 CHEMBL3799558

SMILES COc1ccc(CC(=O)OCC(=O)Nc2c3CCCCc3nc3ccccc23)c(OC)c1OC

InChI Key InChIKey=AYFDPIXHKLCDIY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165323   

TargetAmyloid-beta precursor protein(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50165323(CHEMBL3799558)
Affinity DataIC50: 52nMAssay Description:Inhibition of self-mediated amyloid beta (1 to 42) (unknown origin) aggregation after 24 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50165323(CHEMBL3799558)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50165323(CHEMBL3799558)
Affinity DataIC50: 364nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed