BDBM50165444 2-Amino-5-(4-bromo-3-nitro-phenylsulfanyl)-6-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL195355

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(Br)c(c1)[N+]([O-])=O

InChI Key InChIKey=ZLVSSSHUMLPVPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165444   

TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165444(2-Amino-5-(4-bromo-3-nitro-phenylsulfanyl)-6-methy...)
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165444(2-Amino-5-(4-bromo-3-nitro-phenylsulfanyl)-6-methy...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165444(2-Amino-5-(4-bromo-3-nitro-phenylsulfanyl)-6-methy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory concentration against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed