BDBM50165587 CHEMBL3800298

SMILES COc1ccc(Cn2c(nnc2C(Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)C(Cc2c[nH]c3ccccc23)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(C)=O)cc1

InChI Key InChIKey=WDNCTAOENIQVSW-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165587   

TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50165587(CHEMBL3800298)
Affinity DataKi:  2nM ΔG°:  -11.9kcal/moleT: 2°CAssay Description:Competitive binding affinity to human SNAP-tagged GHS-R1a expressed in HEK293T cells incubated at 4 degC for 3 hrs or at room temperature for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50165587(CHEMBL3800298)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed