BDBM50165706 CHEMBL3797694

SMILES CCC[C@H]1N(CCC[C@@]1(Oc1ccc(cc1)C(F)(F)F)C(=O)N1CCC(CC1)Oc1ncccc1C#N)C(=O)c1cnccc1C(F)(F)F

InChI Key InChIKey=MEKFLEITCCMIQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165706   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165706(CHEMBL3797694)
Affinity DataIC50: 2.40E+3nMAssay Description:Binding affinity to human MDM2 assessed as inhibition of interaction with p53 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed