BDBM50165782 5-Ethyl-1-(4-hydroxy-benzyl)-2-phenylethynyl-7-((R)-phenylmethyl)-7,8-dihydro-1H,5H-imidazo[2,1-b]purin-4-one::CHEMBL362938

SMILES CCN1C2=N[C@H](Cc3ccccc3)CN2c2c(nc(C#Cc3ccccc3)n2Cc2ccc(O)cc2)C1=O

InChI Key InChIKey=HDSXUCHBXDIWDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165782   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165782(5-Ethyl-1-(4-hydroxy-benzyl)-2-phenylethynyl-7-((R...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed