BDBM50166609 CHEMBL3797416

SMILES CCN1CCN(CC1)c1ccc2c(Nc3cc(CCc4cc(OC)cc(OC)c4)[nH]n3)nc(CC)nc2c1

InChI Key InChIKey=JZADASHLALTDDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166609   

TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166609(CHEMBL3797416)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166609(CHEMBL3797416)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166609(CHEMBL3797416)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed