BDBM50166676 3-{5-[2,2-Difluoro-2-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-ethoxy]-indol-1-yl}-3-pyridin-3-yl-propionic acid::CHEMBL362929

SMILES OC(=O)CC(c1cccnc1)n1ccc2cc(OCC(F)(F)c3ccc4CCCNc4n3)ccc12

InChI Key InChIKey=BJFHAMYOMQLVTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166676   

TargetIntegrin alpha-V/beta-3(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50166676(3-{5-[2,2-Difluoro-2-(5,6,7,8-tetrahydro-[1,8]naph...)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed