BDBM50166778 CHEMBL3799140

SMILES COc1cc(CCc2cc(Nc3ncnc4c(Cl)cccc34)n[nH]2)cc(OC)c1

InChI Key InChIKey=KICPMPKKPFQRJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166778   

TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166778(CHEMBL3799140)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166778(CHEMBL3799140)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed