BDBM50168040 CHEMBL3799001

SMILES CNc1ccc(cc1)-n1nc(-c2ccc(OCCCC[P+](c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c2ccccc2c1=O

InChI Key InChIKey=WKXPEFZPEJMHOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168040   

TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50168040(CHEMBL3799001)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of chymotrypsin-like activity of 20S human proteasome assessed as Suc-LLVY-AMC hydrolysis at using Promega proteasome-Glo-3 substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50168040(CHEMBL3799001)
Affinity DataIC50: 1.31E+5nMAssay Description:Inhibition of caspase-like activity of 20S human proteasome assessed as Z-nLPnLD-AMC hydrolysis at using Promega proteasome-Glo-3 substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50168040(CHEMBL3799001)
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of trypsin-like activity of 20S human proteasome assessed as Z-LRR-AMC hydrolysis at using Promega proteasome-Glo-3 substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed