BDBM50168130 CHEMBL3797804

SMILES CCn1c(CNc2ccc(cc2F)C(N)=N)nc2cc(ccc12)C(=O)N(CCC(O)=O)c1ccc(C)c(C)c1

InChI Key InChIKey=RZCXFXIGMCMLSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168130   

TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50168130(CHEMBL3797804)
Affinity DataIC50: 10nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured within 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50168130(CHEMBL3797804)
Affinity DataIC50: 10.1nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured within 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed