BDBM50168319 6-(4-Hydroxy-phenyl)-naphthalen-1-ol::6-(4-hydroxyphenyl)-1-naphthol::CHEMBL193726

SMILES Oc1ccc(cc1)-c1ccc2c(O)cccc2c1

InChI Key InChIKey=MBESMLNJQCOTRU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50168319   

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168319(6-(4-Hydroxy-phenyl)-naphthalen-1-ol | 6-(4-hydrox...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168319(6-(4-Hydroxy-phenyl)-naphthalen-1-ol | 6-(4-hydrox...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168319(6-(4-Hydroxy-phenyl)-naphthalen-1-ol | 6-(4-hydrox...)
Affinity DataIC50: 302nMAssay Description:Inhibition of human placental 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168319(6-(4-Hydroxy-phenyl)-naphthalen-1-ol | 6-(4-hydrox...)
Affinity DataIC50: 302nMAssay Description:Inhibition of [3H]E2 binding to human placental 17beta-HSD2 after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168319(6-(4-Hydroxy-phenyl)-naphthalen-1-ol | 6-(4-hydrox...)
Affinity DataIC50: 302nMAssay Description:Inhibition of human placental microsomal 17beta-HSD2 using [3H]E2 as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168319(6-(4-Hydroxy-phenyl)-naphthalen-1-ol | 6-(4-hydrox...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]E1 as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168319(6-(4-Hydroxy-phenyl)-naphthalen-1-ol | 6-(4-hydrox...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of human placental 17beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168319(6-(4-Hydroxy-phenyl)-naphthalen-1-ol | 6-(4-hydrox...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of [3H]E1 binding to human placental 17beta-HSD1 after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed