BDBM50168328 4-Bromo-7-(3-fluoro-4-hydroxy-phenyl)-3-hydroxy-naphthalene-1-carbonitrile::CHEMBL195039

SMILES Oc1ccc(cc1F)-c1ccc2c(Br)c(O)cc(C#N)c2c1

InChI Key InChIKey=DSGIEWLMQGUMOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168328   

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168328(4-Bromo-7-(3-fluoro-4-hydroxy-phenyl)-3-hydroxy-na...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168328(4-Bromo-7-(3-fluoro-4-hydroxy-phenyl)-3-hydroxy-na...)
Affinity DataIC50: 116nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed