BDBM50168515 CHEMBL185688::N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-2-(2'-methoxy-biphenyl-4-yl)-acetamide

SMILES COc1ccccc1-c1ccc(CC(=O)NC2CCN(Cc3ccc4OCOc4c3)CC2)cc1

InChI Key InChIKey=QBIOYSMPHPCHRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168515   

TargetMelanin-concentrating hormone receptor 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50168515(N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-2...)
Affinity DataIC50: 90nMAssay Description:Inhibition of binding to MCHR1 of human neuronal IMR32-derived cell-line I3.4.2 (Galpha-16 transfected)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50168515(N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-2...)
Affinity DataIC50: 530nMAssay Description:Inhibitory concentration required for functional antagonism of MCH mediated Ca+2 release competing human IMR32 cells receptor in a FLIPRTM based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed