BDBM50168900 CHEMBL3805107

SMILES CCNc1ccc(cc1)C(=O)Nc1cccc(COc2cncc(c2)C(N)=O)c1

InChI Key InChIKey=BDYWFVXKSYJXAM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168900   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50168900(CHEMBL3805107)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50168900(CHEMBL3805107)
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT1 (1 to 747 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50168900(CHEMBL3805107)
Affinity DataIC50: 5.59E+3nMAssay Description:Inhibition of human SIRT3 (102 to 399 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate incubated for 2 hrs by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed