BDBM50168955 CHEMBL3805682

SMILES O=C(NC1(CCCCC1)C(=O)NCC#N)c1ccc(cc1)-c1noc(n1)-c1cccs1

InChI Key InChIKey=TYGJZXJBFCANQH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168955   

TargetCathepsin B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50168955(CHEMBL3805682)
Affinity DataKi: >330nMpH: 6.0Assay Description:Inhibition of human liver cathepsin B using Cbz-Arg-Arg-pNA as substrate at pH 6 incubated for 30 mins measured for 20 mins by photometrical analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50168955(CHEMBL3805682)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-pNA as substrate measured after 10 to 80 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed