BDBM50169062 CHEMBL3805194

SMILES NC(=O)c1cc2c(Oc3ccc(Cl)cc3)cnc(N)c2s1

InChI Key InChIKey=ZMWFSXAKXCNWGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169062   

TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169062(CHEMBL3805194)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169062(CHEMBL3805194)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full length human recombinant His-tagged CDK9/Cyclin T expressed in baculovirus expression system using Cdk7/9tide as substrate by adap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed