BDBM50169237 (S)-(2-Isopropyl-3-oxo-5,7-dipropyl-2,3-dihydro-benzo[d]isoxazol-6-yloxy)-(4-isopropyl-phenyl)-acetic acid::CHEMBL191556

SMILES CCCc1cc2c(on(C(C)C)c2=O)c(CCC)c1O[C@H](C(O)=O)c1ccc(cc1)C(C)C

InChI Key InChIKey=LAFWUMIZQZGZAR-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169237   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169237((S)-(2-Isopropyl-3-oxo-5,7-dipropyl-2,3-dihydro-be...)
Affinity DataIC50: 160nMAssay Description:In vitro binding affinity for human PPAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169237((S)-(2-Isopropyl-3-oxo-5,7-dipropyl-2,3-dihydro-be...)
Affinity DataIC50: 230nMAssay Description:In vitro binding affinity for human PPAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169237((S)-(2-Isopropyl-3-oxo-5,7-dipropyl-2,3-dihydro-be...)
Affinity DataEC50:  270nMAssay Description:Agonist response against human PPAR alpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169237((S)-(2-Isopropyl-3-oxo-5,7-dipropyl-2,3-dihydro-be...)
Affinity DataEC50:  430nMAssay Description:Agonist response against human PPAR gamma in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed