BDBM50169372 1-(3,5-Dichloro-phenyl)-3-[4-(3'-formyl-biphenyl-4-yl)-1-methyl-piperidin-4-ylmethyl]-urea::CHEMBL360731

SMILES CN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(cc1)-c1cccc(C=O)c1

InChI Key InChIKey=VLFGKNPSRVKEEZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169372   

TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50169372(1-(3,5-Dichloro-phenyl)-3-[4-(3'-formyl-biphenyl-4...)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50169372(1-(3,5-Dichloro-phenyl)-3-[4-(3'-formyl-biphenyl-4...)
Affinity DataKi:  5.5nMAssay Description:Ability to displace [125I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed