BDBM50169869 2-[3-(1-Diethylamino-ethyl)-phenoxy]-5,6-dimethoxy-indan-1-one::CHEMBL180640

SMILES CCN(CC)C(C)c1cccc(OC2Cc3cc(OC)c(OC)cc3C2=O)c1

InChI Key InChIKey=YSIMPMRBLCPSEO-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169869   

TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50169869(2-[3-(1-Diethylamino-ethyl)-phenoxy]-5,6-dimethoxy...)
Affinity DataIC50: 1.36E+3nMAssay Description:In vitro inhibitory concentration against rat cortex acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50169869(2-[3-(1-Diethylamino-ethyl)-phenoxy]-5,6-dimethoxy...)
Affinity DataIC50: 1.99E+5nMAssay Description:In vitro inhibitory concentration against butyrylcholinesterase was determined using rat serum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50169869(2-[3-(1-Diethylamino-ethyl)-phenoxy]-5,6-dimethoxy...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of acetylcholinesterase in Rattus norvegicus (rat) cortex by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50169869(2-[3-(1-Diethylamino-ethyl)-phenoxy]-5,6-dimethoxy...)
Affinity DataKi:  865nMAssay Description:Binding affinity to acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article