BDBM50170149 (3,4-Difluoro-phenyl)-{2-[(E)-2-(3,4-dihydroxy-phenyl)-vinyl]-8-hydroxy-quinolin-7-yl}-methanone::CHEMBL189715::US20250213569, Compound 93

SMILES Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4ccc(F)c(F)c4)c(O)c3n2)cc1O

InChI Key InChIKey=XCCXVYPNNNPHQC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170149   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Unité

Curated by ChEMBL
LigandPNGBDBM50170149((3,4-Difluoro-phenyl)-{2-[(E)-2-(3,4-dihydroxy-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against HIV-1 recombinant integrase activity in strand transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Unité

Curated by ChEMBL
LigandPNGBDBM50170149((3,4-Difluoro-phenyl)-{2-[(E)-2-(3,4-dihydroxy-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against HIV-1 recombinant integrase activity in standard 3'-processing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
New York University

US Patent
LigandPNGBDBM50170149((3,4-Difluoro-phenyl)-{2-[(E)-2-(3,4-dihydroxy-phe...)
Affinity DataIC50: 7.65E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent