BDBM50170669 (3S,4aR,4bS,6S,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5-dioxo-6-phenylcarbamoyloxy-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester::CHEMBL190785

SMILES COC(=O)[C@@H]1C[C@H](OC(=O)Nc2ccccc2)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1

InChI Key InChIKey=IHDOVLHHTAJFKU-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50170669   

TargetKappa-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50170669((3S,4aR,4bS,6S,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dim...)
Affinity DataEC50:  480nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor kappa1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50170669((3S,4aR,4bS,6S,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dim...)
Affinity DataEC50:  2.53E+3nMAssay Description:Stimulation of [35S]-GTP gammaS binding to Opioid receptor delta 1 expressed in CHO cells; ND = Not determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50170669((3S,4aR,4bS,6S,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dim...)
Affinity DataEC50:  590nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor mu1 expressed in CHO cells; ND = Not determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50170669((3S,4aR,4bS,6S,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dim...)
Affinity DataKi:  16nMAssay Description:Inhibition of [125I]- IOXY binding to human Opioid receptor mu1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50170669((3S,4aR,4bS,6S,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dim...)
Affinity DataKi:  93nMAssay Description:Inhibition of [125I]- IOXY binding to human Opioid receptor kappa1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50170669((3S,4aR,4bS,6S,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dim...)
Affinity DataKi:  230nMAssay Description:Inhibition of [125I]- IOXY binding to human Opioid receptor delta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed