BDBM50171021 4-[3-(2-Dimethylamino-ethyl)-thioureido]-benzenesulfonamide::CHEMBL179218

SMILES CN(C)CCNC(=S)Nc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=SGYDCWZOMUMRHB-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50171021   

TargetAcetylcholinesterase(African malaria mosquito)
Ume£

Curated by ChEMBL
LigandPNGBDBM50171021(4-[3-(2-Dimethylamino-ethyl)-thioureido]-benzenesu...)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of AChE1 in Anopheles gambiae body extract using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Ume£

Curated by ChEMBL
LigandPNGBDBM50171021(4-[3-(2-Dimethylamino-ethyl)-thioureido]-benzenesu...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293F cells using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi

Curated by ChEMBL
LigandPNGBDBM50171021(4-[3-(2-Dimethylamino-ethyl)-thioureido]-benzenesu...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against catalytic domain of human carbonic anhydrase XIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

Curated by ChEMBL
LigandPNGBDBM50171021(4-[3-(2-Dimethylamino-ethyl)-thioureido]-benzenesu...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

Curated by ChEMBL
LigandPNGBDBM50171021(4-[3-(2-Dimethylamino-ethyl)-thioureido]-benzenesu...)
Affinity DataKi:  100nMAssay Description:Inhibitory activity against human carbonic anhydrase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed