BDBM50171206 CHEMBL3805919

SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Br)ccc2oc1=O

InChI Key InChIKey=VBUCMEPVXZQACZ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50171206   

TargetCarbonic anhydrase 12(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50171206(CHEMBL3805919)
Affinity DataKi:  0.620nMAssay Description:Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50171206(CHEMBL3805919)
Affinity DataKi:  22nMAssay Description:Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50171206(CHEMBL3805919)
Affinity DataKi:  24nMAssay Description:Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50171206(CHEMBL3805919)
Affinity DataKi:  24nMAssay Description:Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50171206(CHEMBL3805919)
Affinity DataKi:  40nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50171206(CHEMBL3805919)
Affinity DataKi:  56nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50171206(CHEMBL3805919)
Affinity DataKi:  160nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50171206(CHEMBL3805919)
Affinity DataKi:  1.75E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed