BDBM50171317 5-(1-Ethyl-propyl)-7-methyl-1-(4-trifluoromethyl-phenyl)-4,5-dihydro-1H,3H-1,2a,5,8-tetraaza-acenaphthylen-2-one::CHEMBL364037

SMILES CCC(CC)N1CCn2c3c1cc(C)nc3n(-c1ccc(cc1)C(F)(F)F)c2=O

InChI Key InChIKey=XOTPNDIXHQGKHW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171317   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50171317(5-(1-Ethyl-propyl)-7-methyl-1-(4-trifluoromethyl-p...)
Affinity DataKi:  170nMAssay Description:Binding affinity for corticotropin-releasing factor-1 expressed in leukocyte tyrosine kinase cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed