BDBM50171414 5-Chloro-2-[5-(3-chloro-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-pyridine::CHEMBL361702

SMILES Clc1ccsc1-c1nc(no1)-c1ccc(Cl)cn1

InChI Key InChIKey=QLWZGYISUDNRSA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171414   

TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171414(5-Chloro-2-[5-(3-chloro-thiophen-2-yl)-[1,2,4]oxad...)
Affinity DataEC50:  390nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171414(5-Chloro-2-[5-(3-chloro-thiophen-2-yl)-[1,2,4]oxad...)
Affinity DataEC50:  1.59E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171414(5-Chloro-2-[5-(3-chloro-thiophen-2-yl)-[1,2,4]oxad...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed