BDBM50171556 (R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic acid::(S)-2-Amino-N-(2,2-dihydroxide-boron-ethyl)-3-methyl-butyramide::CHEMBL365322

SMILES CC(C)[C@H](N)C(=O)N[C@@H](C)B(O)O

InChI Key InChIKey=SHQGMGKBRGBIGM-UHFFFAOYSA-N

Data  3 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50171556   

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataIC50: 3.5nMpH: 2.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataIC50: 9nMpH: 8.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory concentration against human fibroblast activation protein alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataIC50: 670nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 8 using FP-TAMRA incubated for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 9 using FP-TAMRA incubated for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataIC50: 0.890nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50171556((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...)
Affinity DataKi:  96nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed