BDBM50171844 3-{4-[8-tert-Butyl-3-(3-chloro-phenyl)-2-oxo-1,3-diaza-spiro[4.5]dec-1-ylmethyl]-benzoylamino}-propionic acid::CHEMBL198094

SMILES CC(C)(C)C1CCC2(CN(C(=O)N2Cc2ccc(cc2)C(=O)NCCC(O)=O)c2cccc(Cl)c2)CC1

InChI Key InChIKey=ZFEIFXVZUAQWMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171844   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171844(3-{4-[8-tert-Butyl-3-(3-chloro-phenyl)-2-oxo-1,3-d...)
Affinity DataIC50: 601nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171844(3-{4-[8-tert-Butyl-3-(3-chloro-phenyl)-2-oxo-1,3-d...)
Affinity DataIC50: 351nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed