BDBM50171986 5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-2,3-dihydro-benzofuran-2-carboxylic acid::CHEMBL363154

SMILES OC(=O)C1Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1

InChI Key InChIKey=QBESIOYKBFOJER-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50171986   

TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171986(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity for PPAR-deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171986(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataEC50: >3.00E+3nMAssay Description:Effective concentration against human PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171986(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity for PPAR-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Dog)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171986(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataEC50:  1.35E+3nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed