BDBM50172019 5-[2-Benzyl-4-(5-fluoro-2-methoxy-phenyl)-2-hydroxy-4-methyl-pentylamino]-3H-isobenzofuran-1-one::CHEMBL197100

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2C(=O)OCc2c1)Cc1ccccc1

InChI Key InChIKey=QQFIDVOPZHXZPF-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172019   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172019(5-[2-Benzyl-4-(5-fluoro-2-methoxy-phenyl)-2-hydrox...)
Affinity DataIC50: 81nMAssay Description:Binding affinity towards glucocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172019(5-[2-Benzyl-4-(5-fluoro-2-methoxy-phenyl)-2-hydrox...)
Affinity DataIC50: 195nMAssay Description:Binding affinity towards mineralocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172019(5-[2-Benzyl-4-(5-fluoro-2-methoxy-phenyl)-2-hydrox...)
Affinity DataEC50:  610nMAssay Description:Effective concentration against inhibition of Dexamethasone induced glucocorticoid receptor transactivation of mouse mammary tumor virus luciferase g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172019(5-[2-Benzyl-4-(5-fluoro-2-methoxy-phenyl)-2-hydrox...)
Affinity DataIC50: 80nMAssay Description:Binding affinity towards progesterone receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed