BDBM50172262 1-(5-Chloro-3-methyl-pyrazol-1-ylmethanesulfonyl)-3-(1,2,5,6-tetrahydro-pyridin-3-yl)-1H-indole::CHEMBL197845

SMILES Cc1cc(Cl)n(CS(=O)(=O)n2cc(C3=CCCNC3)c3ccccc23)n1

InChI Key InChIKey=GAYQDWLUBHUGLY-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172262   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172262(1-(5-Chloro-3-methyl-pyrazol-1-ylmethanesulfonyl)-...)
Affinity DataEC50:  89.5nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172262(1-(5-Chloro-3-methyl-pyrazol-1-ylmethanesulfonyl)-...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed