BDBM50172646 CHEMBL3809583

SMILES CN(C)C(=O)c1ccc(cc1Cl)-c1cnc(N2CCN(CC2)C(=O)OC(C)(C)C)c(c1)C#N

InChI Key InChIKey=GGBFPOANZPHQBF-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172646   

TargetOxysterols receptor LXR-alpha(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50172646(CHEMBL3809583)
Affinity DataEC50:  280nMAssay Description:Agonist activity at LXRalpha (unknown origin) expressed in human HepG2 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50172646(CHEMBL3809583)
Affinity DataEC50:  770nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50172646(CHEMBL3809583)
Affinity DataEC50:  940nMAssay Description:Agonist activity at GST-tagged LXRbeta-LBD (unknown origin) by LanthaScreen TR-FRET liver X receptor coactivator assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50172646(CHEMBL3809583)
Affinity DataEC50:  1.48E+3nMAssay Description:Agonist activity at GST-tagged LXRalpha-LBD (unknown origin) by LanthaScreen TR-FRET liver X receptor coactivator assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed