BDBM501729 N-Cyclopentyl-3-(5-((5-(2-(dimethylamino)ethoxy)-7-methyl-9-oxo-9H-xanthen-3-yl)thio)pyridin-2-yl)propanamide::US11028064, Example 43

SMILES CN(C)CCOc1cc(C)cc2c1oc1cc(Sc3ccc(CCC(=O)NC4CCCC4)nc3)ccc1c2=O

InChI Key InChIKey=XWULHVZEQQALBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501729   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM501729(N-Cyclopentyl-3-(5-((5-(2-(dimethylamino)ethoxy)-7...)
Affinity DataIC50: 100nMAssay Description:IC50 values were determined using the Z′-LYTE activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM501729(N-Cyclopentyl-3-(5-((5-(2-(dimethylamino)ethoxy)-7...)
Affinity DataIC50: 5.50E+3nMAssay Description:IC50 values were determined using the Z′-LYTE activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent