BDBM50173190 3-(8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazin-6-yl)-N-[2-(4-hydroxy-phenyl)-ethyl]-benzamide::CHEMBL193733

SMILES Nc1nc(cn2nc(nc12)-c1ccco1)-c1cccc(c1)C(=O)NCCc1ccc(O)cc1

InChI Key InChIKey=HSIJAPBQLXLZLC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173190   

TargetAdenosine receptor A2a(Rat)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50173190(3-(8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyra...)
Affinity DataKi:  180nMAssay Description:Binding affinity towards adenosine A2a receptor of rat brain homogenates using [3H]ZM-241385 compared to SCH-58261 (Ki=37 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50173190(3-(8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyra...)
Affinity DataKi: >250nMAssay Description:Binding affinity towards adenosine A1 receptor of rat cerebral cortex using [3H]DPCPX compared to SCH-58261 (Ki=390 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed