BDBM50173196 CHEMBL194244::[3-(8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazin-6-yl)-phenyl]-(4-benzyl-piperazin-1-yl)-methanone

SMILES Nc1nc(cn2nc(nc12)-c1ccco1)-c1cccc(c1)C(=O)N1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=VSUCCGXUIGLIFT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173196   

TargetAdenosine receptor A1(Rat)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50173196([3-(8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyr...)
Affinity DataKi: >250nMAssay Description:Binding affinity towards adenosine A1 receptor of rat cerebral cortex using [3H]DPCPX compared to SCH-58261 (Ki=390 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50173196([3-(8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyr...)
Affinity DataKi:  680nMAssay Description:Binding affinity towards adenosine A2a receptor of rat brain homogenates using [3H]ZM-241385 compared to SCH-58261 (Ki=37 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed