BDBM50173351 1-(4-tert-Butyl-phenyl)-5-(1H-pyrrol-2-yloxy)-3-(3-trifluoromethyl-phenoxy)-1H-indole-2-carboxylic acid::CHEMBL198269

SMILES CC(C)(C)c1ccc(cc1)-n1c(C(O)=O)c(Oc2cccc(c2)C(F)(F)F)c2cc(Oc3ccc[nH]3)ccc12

InChI Key InChIKey=CKICIGYCPKEFTC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173351   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173351(1-(4-tert-Butyl-phenyl)-5-(1H-pyrrol-2-yloxy)-3-(3...)
Affinity DataEC50:  126nMAssay Description:Effective agonist concentration for human PPAR gamma Gal4 construct in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173351(1-(4-tert-Butyl-phenyl)-5-(1H-pyrrol-2-yloxy)-3-(3...)
Affinity DataIC50: 9.02E+3nMAssay Description:Inhibitory concentration against human peroxisome proliferator activated receptor alpha in SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173351(1-(4-tert-Butyl-phenyl)-5-(1H-pyrrol-2-yloxy)-3-(3...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against human peroxisome proliferator activated receptor gamma in SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed