BDBM50173403 4-Methyl-2-[2,2,2-trifluoro-1-(4'-piperazin-1-yl-biphenyl-4-yl)-ethylamino]-pentanoic acid cyanomethyl-amide::CHEMBL195505

SMILES CC(C)CC(NC(c1ccc(cc1)-c1ccc(cc1)N1CCNCC1)C(F)(F)F)C(=O)NCC#N

InChI Key InChIKey=RSIVRPBUNKODPD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50173403   

TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173403(4-Methyl-2-[2,2,2-trifluoro-1-(4'-piperazin-1-yl-b...)
Affinity DataIC50: 902nMAssay Description:Inhibitory activity against cathepsin S from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173403(4-Methyl-2-[2,2,2-trifluoro-1-(4'-piperazin-1-yl-b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against cathepsin B from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173403(4-Methyl-2-[2,2,2-trifluoro-1-(4'-piperazin-1-yl-b...)
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against cathepsin K using humanized rabbit enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173403(4-Methyl-2-[2,2,2-trifluoro-1-(4'-piperazin-1-yl-b...)
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against cathepsin L from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed