BDBM50173405 (S)-2-[1-(4-Bromo-phenyl)-2,2,2-trifluoro-ethylamino]-4-methyl-pentanoic acid cyanomethyl-amide::CHEMBL372979

SMILES CC(C)C[C@H](NC(c1ccc(Br)cc1)C(F)(F)F)C(=O)NCC#N

InChI Key InChIKey=VPRPGHWVFIVNRD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50173405   

TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173405((S)-2-[1-(4-Bromo-phenyl)-2,2,2-trifluoro-ethylami...)
Affinity DataIC50: 0.900nMAssay Description:Inhibitory activity against cathepsin K from humanized rabbit enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173405((S)-2-[1-(4-Bromo-phenyl)-2,2,2-trifluoro-ethylami...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against cathepsin K using humanized rabbit enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173405((S)-2-[1-(4-Bromo-phenyl)-2,2,2-trifluoro-ethylami...)
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibitory activity against cathepsin B from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173405((S)-2-[1-(4-Bromo-phenyl)-2,2,2-trifluoro-ethylami...)
Affinity DataIC50: 121nMAssay Description:Inhibitory activity against cathepsin S from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173405((S)-2-[1-(4-Bromo-phenyl)-2,2,2-trifluoro-ethylami...)
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against cathepsin L from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed