BDBM50173453 6-Chloro-4-[1-(2,2-difluoro-benzo[1,3]dioxol-5-ylmethyl)-piperidin-4-ylamino]-chromen-2-one::CHEMBL194292

SMILES FC1(F)Oc2ccc(CN3CCC(CC3)Nc3cc(=O)oc4ccc(Cl)cc34)cc2O1

InChI Key InChIKey=KSHGPOSCFJFCQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173453   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173453(6-Chloro-4-[1-(2,2-difluoro-benzo[1,3]dioxol-5-ylm...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]MCHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173453(6-Chloro-4-[1-(2,2-difluoro-benzo[1,3]dioxol-5-ylm...)
Affinity DataIC50: 581nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed