BDBM50173587 CHEMBL3809643

SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2ccn(C(=O)Nc3cc(on3)C3(CC3)C(F)(F)F)c2c1

InChI Key InChIKey=DGXSRGYPTXLONO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173587   

TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50173587(CHEMBL3809643)
Affinity DataIC50: 134nMAssay Description:Inhibition of Tel fused KDR (unknown origin) expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50173587(CHEMBL3809643)
Affinity DataIC50: 160nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50173587(CHEMBL3809643)
Affinity DataIC50: 8.60E+3nMAssay Description:Binding affinity to human ERG by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed