BDBM50173696 5-(3-Bromo-phenyl)-3-isopropoxy-pyridazine::CHEMBL383788

SMILES CC(C)Oc1cc(cnn1)-c1cccc(Br)c1

InChI Key InChIKey=QSBFNERLQPXCDQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173696   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173696(5-(3-Bromo-phenyl)-3-isopropoxy-pyridazine | CHEMB...)
Affinity DataKi:  26nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric acid A receptor alpha-1-beta-3-gamma-2 expressed in mouse fibrobla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173696(5-(3-Bromo-phenyl)-3-isopropoxy-pyridazine | CHEMB...)
Affinity DataKi:  36nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in mouse fibrobla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173696(5-(3-Bromo-phenyl)-3-isopropoxy-pyridazine | CHEMB...)
Affinity DataKi:  60nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in mouse fibrobla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed