BDBM50173830 (S)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylethylamino)-1,7-naphthyridine-3-carbonitrile::CHEMBL370336

SMILES C[C@H](Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N)c1ccccc1

InChI Key InChIKey=OBDVISXWHNTJLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173830   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173830((S)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibitory activity against human Tpl2 kinase via quantification of MEK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173830((S)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human Tpl2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed